This book integrates the current state of knowledge on the association of neurochemical and psychological factors underlying the concept of depression or on the process and nature of the drug-induced changes that lead to recovery. Highlighting the results of two major multisite collaborative studies of the psychobiology of depression, the author demonstrates how more refined clinical methods uncover the initial behavioral actions of the drugs and chart the time course of their actions. The results disconfirm earlier textbook reported findings that these actions are...
This book integrates the current state of knowledge on the association of neurochemical and psychological factors underlying the ...
This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new...
This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antid...
