Sir Dominic Corrigan's classic monograph "On Permanent Patency of the Mouth of the Aorta, or Inadequacy of the Aortic Valves" was published in 1832. Descriptions of aortic regurgitation had previously been published by others, but Corrigan's contribution was so comprehensive that his name is still closely associated with this disorder. He described the physical findings and the underlying gross pathologic anatomy of aortic regurgitation. He recognized that sudden death was not characteristic of aortic regurgitation, as it was in aortic stenosis, and his therapeutic approach was based on firm...

Cardiac anatomy had already been a subject of and its control in health and disease has been great interest for centuries when Harvey de published. Studies of hypertrophy, heart failure, scribed the dynamic nature of blood flow, but ischemia, and infarction have been vigorously the concept of defining ventricular function was pursued in experimental animals and in human first introduced with the measurement of a subjects, and as a result new areas for study have emerged. These include the process of hypertro mare's blood pressure by Steven Hales in 1733. Amidst the important contributions of...