Many modern geneticists attempt to elucidate the molecular basis of phenotype by utilizing a battery of techniques derived from physical chemistry on subcellular components isolated from various species of organisms. Volume 5 of the Handbook of Genetics provides explanations of the advantages and shortcomings of some of these revolutionary tech- niques, and the nonspecialist is alerted to key research papers, reviews, and reference works. Much of the text deals with the structure and func- tioning of the molecules bearing genetic information which reside in the nucleus and with the processing...