To study the phenomenon of disease without books is to sail an uncharted sea. While to study books without patients is not to go to sea at all. Sir William Osler Over a period of five years, the impact of computed tomography (CT) on pediatric neuroradiology at The Hospital for Sick Children, Toronto, has been, as expected, in the assessment of the brain and its abnormalities. Concurrent with this application was the introduction of Metrizamide (Amipaque, Nyegaard & Co. AS, Oslo, Norway), a water-soluble CSF contrast medium, used primarily as a myelog raphic agent. The subsequent application...