What do we know about reading comprehension-and what do we need to know in order to improve it and help all students become confident readers? This urgently needed research volume is the only cohesive, up-to-date compendium of knowledge about the behavioral, neurobiological, and genetic components of reading comprehension. More than 40 top researchers from multiple disciplines present the latest findings on comprehension, addressing theory and science, effective instruction and intervention, and priorities for future research that will move the field forward.