Affective disorders are among the most common mental disorders. In a society comparable to the Danish, it is estimated that 3-7% of the population at any given time meets the diagnostic criteria of affective disorders. The physician treating these diseases faces several problems, apart from diagnostic difficulties and side effects of the drugs. One serious problem is delayed clinical efficacy of pharmacological therapy. The period between the direct pharmacological effect and the clinical effects seems to characterize all known antidepressants to sone extent. Another major problem is the...