Cellular editing of RNA can lead to the recoding of expressed sequences before they mature to their functional gene products, such as proteins or regulatory RNAs, and represents a hidden layer of genetic information and regulation. Often, the recoding events are essential for the normal function of the gene product (for example creating an open reading frame), in other cases RNA editing creates additional variation and phenotypic diversity since both the edited and the non-edited versions of the product are functional and co-exist. It is necessary to understand the mechanisms of RNA editing...
Cellular editing of RNA can lead to the recoding of expressed sequences before they mature to their functional gene products, such as proteins or regu...