Genome of PRSV pathotypes P (10317 nt) and W (10335 nt) from India were completely sequenced. Their genome architecture was similar to other 15 isloates from the rest of the world. Comparative sequence analysis revealed that pathotypes P and W shared high degree of sequence identity both at nucleotide (89%) and aminoacid (94%) levels. Sequence comparison of individual cistrons (except P1) also revealed similar trend. The P1 region was most divergent (upto 33%) and this could be attributed to geographical and host adaptation of PRSV. Cistron by cistron sequence comparison of PRSV pathotypes P...