The term diabetes mellitus describes a metabolic disorder of multiple aetiology characterized by chronic hyperglycemia with disturbances of carbohydrate, protein and fat metabolism resulting from defects in insulin secretion, insulin action or both. It is a leading public healthcare problem with increasing incidence and long term complications of various organs such as kidney, neuron, eye, heart. These complications are mainly a consequence of macro and micro vascular damages of the target organs and also associated with ongoing malfunction of them . The prevalence of diabetes is increasing...