Oral drug delivery systems being the most cost-effective and leads the worldwide drug delivery market. The major problem in oral drug system is low and erratic bioavailability, which mainly results from poor aqueous solubility. This may lead to high inter and intra subject variability, lack of dose proportionality and therapeutic failure. For the improvement of bio-availability of drugs with such properties presents one of the greatest challenges in drug formulations. Various technological strategies are reported in the literature including solid dispersions, cyclodextrines complex formation...