L-Asparaginase is widely used enzyme for the treatment of ALL and thus its Production and activity plays a major role in its therapeutic use. Screening of the different sources for prominent L-Asn-ase production and high activity was done at different physiological conditions and high yield of the enzyme was obtained. The obtained enzyme from the two isolates are compared relatively on the basis of Km and Vmax values and one of them is being found to be more effective with low Km. This would serve as a good drug if tested and certified clinically restricting the ALL.

Computational Chemistry Methodology in Structural Biology and Materials Sciences provides a selection of new research in theoretical and experimental chemistry, focusing on topics in the materials science and biological activity.

Part 1, on Computational Chemistry Methodology in Biological Activity, of the book emphasizes presents new developments in the domain of theoretical and computational chemistry and its applications to bioactive molecules. It looks at various aspects of density functional theory and other issues. Part 2, on Computational Chemistry...