Post operative pain is induced by peripheral and central sensitization of structures involved in nociception. Pain can be minimized by the use of analgesic drugs prior to pain stimulation such as surgery. Inhibition of cyclooxygenase -2 (cox - 2) activity leads to reduction in prostaglandin production and its effect in inflammation and pain. In this book an experimental study was done on the inhibition of fracture healing possibly resulting from cyclooxygenase - 2 inhibition by Celecoxib. The orthopaedic community embraced the coxibs as a result of their effectiveness and favorable side...