The eco-friendly solvent-free approach using microwave irradiation opens numerous possibilities for conducting rapid heterocyclic synthesis, via cycloaddition and cyclocondensation reactions, using a variety of supported reagents on mineral oxides and phase transfer catalysis conditions. The absence of solvent reduces considerably the reaction time and generally improves the yields. Due to the wide range of applications of microwaves, this method of synthesis has been selected. Pyrazolines are also known to possess antioxidant property wherein they scavenge free radicals which are one of the...

Mass Spectrometry is a technique that determines the molecular weight (mass) and elemental composition of a compound accurately. It records relative abundance (number of different kinds of ions) and mass/charge (m/e) ratio. An advantage of Mass Spectrometry is its ability to identify the unknown compounds using only pictogram (10-12) amounts. Because ions are very reactive and short-lived, their formation and manipulation must be conducted in a vacuum. Atmospheric pressure is around 760 torr (mm of mercury). The pressure under which ions may be handled is roughly 10-5 to 10-8 torr (less than...