The new design of an Impedance measurement based sensor is integrated into the standard 96 wells microtiter plate which is use for characterizing different stimulus hydrogels. The online monitoring of swelling and deswelling of hydrogel is possible with this new system. Hydrogels of Poly-Hydroxyethyle Methacrylate, Poly (HEMA) with different compositions of mixing monomers were used for measurements. These hydrogels which absorbs/desorbs solution in response to changes in surrounding environmental condition polymerized over the sensor with roughly 200m height. The sensor output voltage...