Cancer is one of the most formidable health problems facing mankind today. High serum glycoprotein values are well documented in cancer patients & reported to be correlated with clinical staging, prognosis & early recurrence in cancer patients. Study was aimed to know prognostic significance of glycoproteins (Protein Bound Hexose PBH, Fucose and Total Sialic acid TSA) in oral cancer patients. Total of 56 patients with different stages of oral cancer & 20 healthy individuals were selected at random & subjected to biochemical analysis. 31 patients were available for 6 months & 1 year follow up....

The normal adult epidermis is a self renewing tissue consisting primarily of 10 to 20 layers in which cell proliferation is primarily restricted to the basal layer.The oral mucosa is a useful tissue to investigate the expression of differentiation linked molecules as it supports a broad range of epithelial differentiation within a relatively confined area. So an attractive approach to explore the molecular perturbation leading to an epidermal or an oral lesion is to investigate the expression of keratin genes in these lesions. Therefore a short review of keratin expression in normal epithelia...