The art of medicine becomes science when supported by evidence. The recommended practices of infection prevention are based on scientific and epidemiologic evidence. However, most health care professionals see them as mandates and fail to incorporate them into their routine patient care activities. The core goal of this publication is to link the practices to the principles they are based on. The expectation is that understanding of the principles will change the practices from mandates to "should do" in the minds of health care professionals. This will lead to improvement in health care...