The aim of this study was to design and evaluate a colon targeting delivery for fenoprofen calcium with better benefits in treating the arthritis. Compression coated tablets were prepared by using guar gum as a coating material over core tablets. These systems would benefit for the high amount release of the drug in the distal intestinal or the colon, this may exhibit better fenoprofen calcium toward the arthritis by reduce the serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine or large intestine. Plan of...