Several sulphur & nitrogen containing heterocyclic compounds have been studied because of their interesting biological properties such as Anti-bacterial, Anti-fungal, Anti-hypertensive, Anti-HIV, Anti-inflammatory, Anti-microbial, Anti-rheumatic, Aldose reductase inhibitor, ATP-sensitive potassium channel opener. 1,4-Benzothiazine forms an important class of heterocyclic system. Several studies are available for 1, 4-Benzothiazine formation and their application in drugs. 1, 4-benzothiazine and thiazoles constitute an important class of sulfur and nitrogen heterocytes. The utility of thiazole...

The primary role of medicinal chemist has become one of improving upon existing drugs by increasing their potency and duration of action and by decreasing toxic side effects as well as creating new drugs by molecular modifications. Very useful synthetic analogue with improved therapeutic properties can be obtained from a single lead compound by structural modification. The same applies to the group of natural lactone of plant origin, one of the diverse and important system of natural products with a broad spectrum biological activities. Physiological activity of natural lactone is known ever...

India has a rich heritage of knowledge on plant based drugs used in traditional system of medicine. A large number of plants and remedies were pharmacologically tested and useful data was generated for development of therapeutic agents. Scientists are searching newer avenues and material for drug development and for that they are search for new medicinal plants, which are till date not have been exploited to their fullest extent (except traditional systems). The rich biodiversity of the tropical region all over the world have attracted scientific attention and tropical region of lower plane...