Life threatening infections caused by pathogenic fungi are becoming increasingly common, especially in individuals with suppressed immune systems. However, there are only a limited number of antifungal drugs available for such infections, which leads to a strong need to develop new classes of compounds having antifungal activity. From the literature survey; it was found that there has been a lot of research going in the field of novel antifungal drug development. It was found that many antifungal agents contain benzimidazole moiety in their structure. Therefore benzimidazole was selected for...

Amongst all carrier utilized for target oriented drug delivery, vesicular drug delivery system in the form of liposome is most extensively investigated. Liposomes are gaining popularity because of their inert biological nature, freedom from antigenic, pyrogenic or allergic reactions and similarity of primary components of liposomes with natural membrane. Human Immunodeficiency Virus (HIV) is a retrovirus that causes irreversible destruction of immune system, leading to occurrence of opportunistic infection and malignancy. During last decade, even though attempts were being made to eradicate...