Bioinformatics is a helpful tool to experimental studies. It is less time consuming and may provide a platform for experimental work. Post translational modification is investigated in silico, with the help of the bioinformatics tool MAPRes. This tool mines association pattern around a modified residue. In this work association rules were mined around methylated Lys/Arg residues in protein. These rules show highest preference for Gly in modified protein Arg and Ser and Gln in modified protein Lys. 75% data support the preference of Gly in methylated Arg with 100% confidence level. 25% data...