Andrographis paniculata (AP) has selected to be developed as an anti-diabetic herbal extract. However, the adverse effect of AP on male reproductive function is still unknown. The present study aims to look at the effects of 50% AP ethanolic extract (APE) on the male Sprague Dawley rats reproductive functions and to see whether it has anti-fertility effects. Four important endpoints were observed i.e. male reproductive performance (MRP), male sexual behavior (MSB), histological toxicity evaluation of male reproductive organs and hormonal level. Sixty adult male rats aged 8-10 weeks were used...