The basic requirements for commercial formulation of solid unit dosage form particularly of tablet and capsule are good flowability, mechanical strength and compressibility and all of these requirements are fulfilled when the drug candidates are in granular or spherical form. Since all drugs does not posses the granular nature so by the help of granulation techniques fine powder can be converted into granules which may lead to some problems like more time consuming and chances of drug excipients interaction. The spherical crystallization technique is revolution in particle engineering...