The use of polymeric matrix devices to control the release of variety of therapeutic agents has become increasingly important in development of the modified release dosage forms. The device may be a swellable, hydrophilic monolithic systems, an erosion controlled monolithic system or a non erodible system. The initial burst release of 5-Fluoruracil from such matrix tablet surface can be controlled by compression coating technology. Appropriate combination of hydrophilic polymer in upper and lower layer of tablet can govern the release of 5-fluoruracil as well as lag time to deliver it in...
The use of polymeric matrix devices to control the release of variety of therapeutic agents has become increasingly important in development of the mo...
