Rotaviral diarrhoea cause 453,000 deaths in children annually and infects all children in the world by the age of five indicating that vaccines offer the best hope of the disease control. Human caliciviruses cause outbreak associated gastroenteritis while astroviruses cause infantile gastroenteritis. New rotavirus vaccines have been developed and introduced in some countries. These vaccines could show reduced effectiveness in countries where "novel" rotavirus strains are common. The assessment of the efficacy of vaccines require reliable data on disease, hence detailed and continuous...
Rotaviral diarrhoea cause 453,000 deaths in children annually and infects all children in the world by the age of five indicating that vaccines offer ...