The differential expression of miRNA in cancer could be useful in diagnosis to distinguish between malignant and reactive lesions. Moreover, given that the complex mechanism of gene regulation by microRNAs is profoundly influenced by variations in gene sequence (polymorphisms) of the target sites; it may indicate that miRNA expression could be influenced not only by tumor type but also by individual variability related to ethnic geographical region. On the other hand, considering critical roles for chromatin-modifying complexes in the establishment and maintenance of cells pluripotency, and...