The thyroid hormones play a pivotal role in the generation of oxidative stress on exposure to stressor. It was further observed that vitamin E treatment eliminated the stress induced oxidative stress while the raised levels of T3 and T4 remained unaffected.The present investigations provided enough evidence to show that the supra spinal response to stress basically elevates the thyroid hormone levels, which onward causes the oxidative stress. Such conclusion further suggests the use of antithyroid agent to prevent the stress induced oxidative stress and subsequent tissue degeneration....