This book highlighted the methods used for the synthesis of some new pyrimidine compounds. The reactivity of pyrimidine and their synthetic importance were investigated. It also reported a good introduction for the literature survey of the chemistry of pyrimidine compounds. In this context, we reported herein the behavior of simple reagents in order to obtain some new pyrimidine ring systems and its reactivity towards different reagents for the constructions of heterocyclic derivatives containing a pyrimidine moiety. The methods of synthesis and the synthetic mechanisms of the aforementioned...