Pain is an unpleasant sensory experience associated with tissue damage. It is usually accompanied by various clinical signs and symptoms. We conducted this study to assess the cardio respiratory changes due to acute cold pain along with Galvanic Skin Resistance. Basal Respiratory parameters-Respiratory rate(RR), Forced Vital Capacity(FVC), Tidal Volume(TV), FEV (Forced Expiratory volume in first second, ERV(Expiratory Reserve Volume), and Peak Expiratory Flow Rate(PEFR) were recorded using the Spirometer-Spirobank G in 30 non smoker medical students. Change in GSR during acute cold pain was...