Amoebiasis is an infection caused by a protozoan parasite called Entamoeba histolytica. In Zaria, the standard of sanitation is low; diarrhoea in children is high with corresponding morbidities and deaths. However, knowledge of the significance of this parasite in children, especially in the light of modern and more sensitive method of diagnosis is not sufficient. An immunoassay of E. histolytica in children aged 3-60 months was carried out using the TechLab E. histolytica II ELISA kit which is specific and sensitive for the parasite, as microscopy alone is no longer reliable. Out of 183...