Light-Cone 2016 belongs to a conference series that started in 1991 under the supervision of the International Light Cone Advisory Committee and showed, year by year, to play a vital role in promoting the research towards a rigorous description of hadrons and nuclei, based on Light-Cone quantization methods. A strong relation with the experimental activity represents an important commitment of the Light-Cone community, with the ambition ''to assist in the development of crucial experimental tests at hadron facilities''. This work is comprised of selected papers presented by researchers...