To meet the demands of exponentially growing global energy consumption, extensive research is necessary for future fusion and Generation IV fission reactor power plants; however, structural material performance is a limiting factor. Conventional materials cannot withstand the complex thermomechanical loading, higher operating temperatures, and high irradiation doses. Consequently, research efforts are underway to develop and qualify novel structural materials. Likewise, research on fuel materials seeks to understand and mitigate issues such as oxidation and evolution of the fuel...