The Purpose of the Present study was to compare the action of glucose and scopolamine on the cognitive function using digital zero maze apparatus on albino rats.The present study 3 groups were taken and had given treatment glucose and scopolamine (buscopan)and Normal Saline.The digital zero maze was design to study animal behavior after supervised training given to the rats.glucose and scopolamine were shows that the glucose a have some sought of cognition enhancing activity inexperiment animals On the other hand the scopolamine slows down cognition activity of brain.

Amlodipine used as an anti-hypertensive and in the treatment of angina. FDT of amlodipine besylate were prepared using different superdisintegrants by direct compression method. Mannitol was used as a diluent. Aspartame and Acesulfame Potassium were used for unpleasant taste masked from the amlodipine by cosifting and serial of blending with other excipients. The mixed final blend was then compressed into tablets. The formulations were evaluated for weight variation, hardness, friability, wetting time, disintegrating time, dissolution, taste evaluation study and in vitro dispersion time.

prepare and evaluate mucoadhesive drug delivery system of Ranitidine hydrochloride tablet using hydrophilic polymers in order to reduce dose frequency to match the initial release of the drug with the conventional dosage form. The formulation was designed adopting optimization technique, which helps in setting up experiments in such a manner that the information is obtained as efficiently and precisely as possible. Initially, considering buoyancy as the main criteria, blank tablets were compressed for different formulae with various polymers HPMC K 15 M, HPMC K 100 M, Carbopol 934. The...

This study was to investigate the effect of formulation variables like Microcrystalline cellulose (MCC), Lactose, Dicalcium phosphate dihydrate (DCPD), Starch 1500, Pearlitol 200sd etc. which are widely used tabeleting excipients. These diluents were used individually and in combination with MCC. Binders like Hydroxypropyl cellulose (HPC-sL), Polyvinylpyrrrolidone-K 30, were used to study their effect on pellet properties. The pellets prepared were analyzed for the properties like their shape (aspect ratio), size distribution, smoothness, bulk density, tapped density, car index, hausner...

Metformin matrix and gastro retentive tablets formulations were prepared with different compositions. Finally, one optimized formula for each, matrix and gastro retentive, were selected and studied in detail. The effect of formulation variables namely, process of manufacturing, different excipients, different polymers, and concentration of polymer were studied. Metformin release was inversely proportional to the polymer concentration. Drug release from the developed formulations was independent of pH of the release medium but dependent on the agitational intensity, hardness of tablet, and...

The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result: -The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs...