"Next generation" sequencing techniques allow for more detailed analysis of exons and introns in multiple genes at the same time. This will reveal manymutations that potentially lead to exon skipping. To functionally test thesea lot can be achieved with a limited set of protocols, while for the intentional induction of exon skipping different tools and target genes are involved and the translational path from in vitro splicing to in vivo tests in animal modelsrequiring a more extensiveset of protocols.Exon Skipping: Methods and Protocols provides scientist with a...
"Next generation" sequencing techniques allow for more detailed analysis of exons and introns in multiple genes at the same time. This will reveal ...
This Methods in Molecular Biology (TM) book reviews methods and techniques used for exon skipping, such as methods on how to distinguish "real polymorphisms" from mutations that affect splicing. Includes protocols, materials lists, pitfalls and troubleshooting tips.
This Methods in Molecular Biology (TM) book reviews methods and techniques used for exon skipping, such as methods on how to distinguish "real polymor...