Breast cancer and its hormone receptor subtypes vary in incidence globally with 5-10 times higher incidence in developed than in developing countries. Most risk factors of breast cancer are environmental involving increased exposure to estrogen. Known risk factors of breast cancer explain only 50% of the risk; other risk factors such as xenoestrogens which are environmental, estrogenic and development-related might be responsible for the remaining risk. We discovered 3-4 times higher incidence of breast cancer and hormone receptor positive breast cancer in urban areas than in rural areas of...