The ability to take up and metabolize nutrients isvitally important for the survival of every livingorganism. Higher organisms need to control theirenergy uptake and expenditure, as a positive energybalance over time can lead to obesity and even earlydeath. The regulation of energy homeostasis, according to the neurocentric model, is performed bya small neuronal subnetwork in the hypothalamus. Thisnetwork comprises, among others, satiety mediating, pro-opiomelanocortin (POMC) expressing neurons andhunger mediating, agouti-related protein (AgRP)expressing neurons. They integrate signals from...