Diabetes mellitus is probably the single most important metabolic disease and is widely recognized as one of the leading causes of death and disability in the different countries of the World. It affects every cell in the body and the essential biochemical processes that go on there. Even in normal individuals, significant weight gain results in carbohydrate intolerance, higher insulin levels and insulin insensitivity in the fat and muscle tissues. Weight loss can correct all of these abnormalities in many instances and ...