Dynamic turnover of microtubules plays a critical role in cell growth and division. This book describes computational models that accurately describe assembly dynamics and energetics within the microtubule polymer lattice. These models serve as tools to investigate the molecular mechanisms underlying observed dynamic polymer reorganization. As a first approach to building a mathematical model that recapitulates the dynamic instability of microtubules, Dr. VanBuren describes a simple Monte Carlo state model able to simulate microtubule growth or shortening. This simple model was used to...