This volume constitutes the refereed proceedings of the 18th EuroSPI conference, held in Roskilde, Denmark, in June 2011. The 18 revised full papers presented together with 9 key notes were carefully reviewed and selected. They are organized in topical sections on SPI and assessments; SPI and implementation; SPI and improvement methods; SPI organization; SPI people/ teams; SPI and reuse; and, selected key notes for SPI implementation.