The resistance of malaria parasites to widely used drugs prompted an upsurge in the development of new drugs with novel mechanism of action, and re- evaluation of the existing drugs to overcome the resistance problem. A number of new potential target pathways have already been identified and efforts to develop lead compounds for these putative targets hopefully will allow treatment of malaria infections in a uniform sustained way. Considerable research efforts were directed in the areas of chloroquine drug resistance reversal agents. Careful development of some bisquinolines, which...

In last few decades interest of researcher and peoples were augmented in cosmetics. Harmful effect of chemicals used in cosmetic preparation gives rise to herbal products in cosmetology. Unlike chemical based products, herbs are by nature more friendly to human body and therefore are completely safe, extremely effective and have almost no negative side effects. They are used in cosmetic for enhancing attractiveness and cleaning purpose. Beside this the standardization of the herbs and quality control of the herbs are very necessary in the cosmetic. Hence the book focuses on the potential of...

In current drug discovery and development field bioanalytical techniques plays an important role in quantitative determination in plasma. Various pharmacokinetics, toxicokinetics, bioequivalence and exposure-response (pharmacokinetics/ pharmacodynamics) are biomedical drug development pursuits that cannot be accomplished without an accurate means of quantifying the moieties that scientists seek to characterize. Many chromatographic techniques immensely used for this. Hence this book comprehensively gives an overview on various important aspects and challenges in bioanalytical techniques....