Pharmacogenetics is generally regarded as the study of genetic variation that gives rise to different responses to drugs. It may be possible to predict therapeutic failures or severe adverse drug reactions in individual patients by testing for important DNA sequence variations or polymorphisms in key drug-metabolizing enzymes, receptors, transporters, etc. In this book, we characterized methods for genotyping CYP3A4*2, CYP3A4*4, CYP3A4*5, CYP3A4*6, and CYP3A4*10 alleles among Bangladeshi population in 70 healthy adult unrelated volunteers. Cytochrome P450 3A (CYP3A) subfamily is responsible...
Pharmacogenetics is generally regarded as the study of genetic variation that gives rise to different responses to drugs. It may be possible to predic...