The aim of the present study was to enhance the dissolution and bioavailability of aceclofenac by using a natural biodegradable polymer, chitosan.Recently, natural polymers such as polysaccharides and proteins have received much attention in the pharmaceutical field owing to their good biocompatibility and biodegradability. Among polysaccharides, chitosan has been considered to be one of the most promising biopolymer for drug delivery systems. The approach was to precipitate chitosan over drug crystals in the presence of a salting out agent sodium citrate, along with micronization of drug...
The aim of the present study was to enhance the dissolution and bioavailability of aceclofenac by using a natural biodegradable polymer, chitosan.Rece...