What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases and are there therapeutic strategies to correct or compensate for its dysfunction? This book addresses these questions, providing an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Current experimental evidence for both evolutionarily...