Sustained release of macromolecular drugs from polymeric matrices has received increasing attention in recent years. Vaccines that are required to be given in multiple divided doses are not efficacious if only one dose is given without boosting. In order to be effective, most vaccines require two or three booster doses after primary immunization. Therefore, the conversion of multiple dose vaccines into single dose vaccines may represent an important advance. Among the various tentative for improving the administration of proteins, the microencapsulation into biodegradable polymers represents...

Wound is defined simply as the disruption of the cellular and anatomic continuity of a tissue. Wound may be produced by physical, chemical, thermal, microbial or immunological insult to the tissue. Attention should be directed towards discovering an agent, which will accelerate wound healing either when it is progressing normally, when it is suppressed by various agents like corticosteroids, anti neoplastics.or non- steroidal anti-inflammatory agents. Medical treatment of wound includes administration of drugs either locally (topical) or systemically (oral or parenteral) in an attempt to aid...

Tablet is the most popular among all dosage forms existing today because of its convenience of self administration, compactness and easy manufacturing; however hand tremors, dysphasia in case of geriatric patients, the underdeveloped muscular and nervous systems in young individuals and h case of uncooperative patients, the problem of swallowing is common phenomenon which leads to poor patient compliance To overcome these drawbacks, mouth dissolving tablets (MDT) or orally disintegrating tablets; (ODT) has emerged as alternative oral dosage forms. These are novel types; of tablets...