Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men.Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological andClinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the...

Studies on Men's Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date. The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a...

This volume covers data describing the role of free radicals and antioxidants that deal with clinical and pre-clinical trials, as well as basic research in the area of women's health. There is increasing evidence that oxidative stress is a causative, or at least a supporting factor in female pathology and infertility. During advancing gestational age, oxidative stress biomakers rise. Oxidative stress plays a regulatory role in transcription, signal transduction, gene expression and membrane trafficking. A search on Pub Med shows 449 papers have been published to date related to women's...

In the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those...

A growing majority of women in the western hemisphere have been delaying initiation of childbearing to later in life. Consequently, more than ever before, women in their late 30s to early 40s are attempting their first pregnancy. Since the incidence of most cancers increases with age, delayed childbearing results in more female cancer survivors interested in fertility preservation. Fertility Preservation in Females: Emerging Technologies and Clinical Applications contains a selection of the valuable chapters and protocols of Seli and Agarwal s previously published hardcover text...

Fertility Preservation in Males: Emerging Technologies and Clinical Applications contains a selection of the valuable chapters and protocols of Seli and Agarwal s previously published hardcover text Fertility Preservation: Emerging Technologies and Clinical Applications. Newly available in this convenient and affordable softcover format, this practical reference guide provides an update on options for fertility preservation in men, while also discussing important related epidemiologic, ethical, medico-legal, psychological, and social aspects. Using a format that combines...

This concise, truncated version of Parekattil and Agarwal's Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants is the first resource dedicated solely to clinicalissues of infertility. With select chapters that will prove invaluable to the reproductive medicine clinician, Male Infertility for the Clinicianaddresses issues like:

- Diagnosis and management of male infertility conditions such as varicocele, ejaculatory duct obstruction and congenital epididymal obstruction

- New approaches to Klinefelter's syndrome

- A concise...

This concise, truncated version of Nagy, Varghese and Agarwal's Practical Manual of In Vitro Fertilization is comprised of select clinical chapters for a portable, affordable and up-to-date resource. Gamete Assessment, Selection and Micromanipulation in ART covers a variety of topics, including:

- Human oocyte evaluation

- Sperm evaluation and selection

- Micromanipulators and micromanipulation

- Biopsy procedures on oocytes and embryos

- Molecular insights in IVF

Practical for both clinicians and researchers alike, Gamete...