The objective of this work is to study the response of this neutrophile in an acidic environment with respect to the activities of isocitrate, malate, succinate and G-6-PD on being coupled to the electron transport chain. E.coli have an optimum pH range of 6 to7 for growth and survival and are hence,called neutrophiles. When challenged by low pH, protons enter the cytoplasm; as a result mechanisms are required to alleviate the effects of lowered cytoplasmic pH. This study highlights new insights into activities of isocitrate, succinate, malate and G-6-PD, coupled to the electron...

Antimicrobial resistance is now threatening the management of infections such as pneumonia, tuberculosis, malaria and AIDS.So at present scenario there is a great need for developing new anti-infective agents.Heterocycles are an inescapable and integral feature of numerous diverse branches of chemistry.The presence of heterocycles in all kinds of organic compounds of interest in biology, pharmacology, optics, electronics, material sciences.Among the heterocyclic compounds, five member heterocyclic moieties fused with aromatic ring system with various heteroatom like N, S, and O have possess...

Solid waste management is a global concern, and landfilling remains the predominant management method in most areas of the world. This book provides a comprehensive view of state-of-the-art methods to manage landfills more sustainably, drawing upon more than two decades of research, design, and operational experiences at operating sites across the world. Sustainable landfills implement one or multiple technologies to control and enhance the degradation of waste materials to realize a multitude of potential benefits during or shortly after the landfill's operating phase. This book presents...

Solid waste management is a global concern, and landfilling remains the predominant management method in most areas of the world. This book provides a comprehensive view of state-of-the-art methods to manage landfills more sustainably, drawing upon more than two decades of research, design, and operational experiences at operating sites across the world. Sustainable landfills implement one or multiple technologies to control and enhance the degradation of waste materials to realize a multitude of potential benefits during or shortly after the landfill's operating phase. This book presents...