This edition of Immunology and Allergy Clinics focuses on Stress and Immune-Based Diseases. Articles include: The Adverse Effects of Psychological Stress on Immunoregulatory Balance: Application to Human Inflammatory Diseases; Impact of Psychological Stress on Chronic Fatigue Syndrome Patients;Stress and Asthma;Stress and Allergic Diseases; Stress and Autoimmune Diseases;Psychosocial influences of Stress in Cancer Patients;Stress and Wound Healing and Neuroendocrine Effects of Stress on Immunity in the Elderly: mpact on Risk for Inflammatory Diseases.