Rapid and efficient wide-scale distribution of medical supplies plays a critical role in assuring the effectiveness in managing the risks of large-scale emergencies such as a bio-terrorism attack. Important issues in the design of such an efficient distribution network involve deciding how to route distribution vehicles and how to manage these inventories. The high uncertainty, limited supply and overwhelming demand associated with a large-scale emergency may result in significant unmet demand, which is a direct representation of the most undesirable consequence - loss of life. Solving...