The present study is an attempt to determine the alterations influencing the premenstrual seizure exacerbation. The epileptic women (n: 433) were categorized into: Group-I (single seizure frequency pattern) and Group-II (multiple seizure frequency pattern). Both groups showed significant decrease in plasma calcium. Catamenial epilepsy groups showed significant rise in the premenstrual estradiol, prolactin, cortisol, sodium, BBT and fall in plasma calcium, all with concomitant significant exacerbation of seizures. Furthermore, plasma progesterone varied significantly only in...