Strains of Salmonella Paratyphi A isolated from the patients admitted to the diarrhoea treatment center of ICDDR, B were characterized both at the phenotypic and genotypic levels. Antibiotic susceptibility test revealed that 61% of the strains (n = 19) were sensitive to all the antibiotics used for empirical treatment of paratyphoid fever and 32% strains (n = 10) were resistant only to nalidixic acid. Most of the strains that showed reduced susceptibility to ciprofloxacin, having elevated MIC value (0.5ug/ml). A point mutation in the gyrA gene was observed at codon 83 (TCC to TTC), which...

A total of 9 experiments were carried out at different doses (100, 200 and 400 mg/kg, p.o.) of Dhatri Lauha(DTR)which was studied in different animal model to find out the various degrees of significant action of the drug on mice (Swiss-Webster strain, 20-40 gm body weight). Highly significant (p=0.009) increase in ambulation behavior was observed in Hole board test and highly significant (p=0.005) increase in motor activity was observed in Hole cross test. Open field test showed significant (p=0.036) increase in Standing up behavior. Climbing out test produced a significant (p=0.039)...

The plant Setaria italica (Family: Poaceae) has been studied for the evaluation of pharmacological activities of the extractives The crude ethanolic extract and its different fractions were screened for various pharmacological properties. In acetic acid induced writhing method, ethanolic crude extract and carbon tetrachloride fraction showed promising analgesic activity. In radiant heat tail-flicking test, anti-nociceptive effect of crude ethanolic extract was found to be moderately significant (with 52-55% elongation of tail flicking time, p>0.01). Ethanolic crude extract (10.33 g/ml),...