This volume of Springer s Lecture Notes in Computer Science series comprises th the scienti?c proceedings of the 10 International Workshop on Digital Mammography (IWDM), which was held June 16 18, 2010 in Girona, Cata- nia. The IWDMmeetingstraditionallybringtogetheradiversesetofresearchers (physicists, mathematicians, computer scientists, engineers), clinicians (radi- ogists, surgeons) and representatives of industry, who are jointly committed to developing technology, not just for its own sake, but to support clinicians in the early detection and subsequent patient management of breast...